
qd rejuran
Rejuran is an injectable skin booster that uses polynucleotides (PN) purified from salmon DNA to support the skin’s own repair and improve texture, fine lines and elasticity. At QD Clinic in Gangnam, Seoul, we offer the Rejuran range — Healer, HB, I and S — and choose the formula and areas after assessing your skin. A session usually takes about 20–40 minutes including numbing. (Results vary by individual.)
is this for me
Who it’s for
Even if none of these describes you, we will look again at the consultation.
- Dull skin, fine lines or early loss of elasticity
- Those who want to improve overall skin quality rather than add volume
- Dry or sensitive skin looking for a hydration and comfort option (HB)
- Concerns around the eyes or depressed scars (I and S)
Which Rejuran formula suits you is confirmed during consultation.
Before you pick a treatment name, start with the cause of your concern.
start with your concern
Even a treatment with the same name takes on a different role and scope depending on your current structure, the change you want, what you have had before and the recovery time you have.
01
Where you are now, and where we start
Skin texture, fine lines and elasticity, and which of Healer, HB, I or S fits
02
The change you want, the impression you keep
Rather than adding more volume, we decide where to fill and where to leave alone, and the line at which expression stays natural.
03
How it differs from similar options
We compare what filler, Botox and skin boosters each change and what they cannot change, with the alternatives alongside them.
04
Health information and recovery schedule
Beforehand we check blood thinners, immune conditions and allergies, past injectables, possible pregnancy and the dates that matter.
the
principle
Before the product name we match the actual ingredients, the injection layer and your skin concern, then decide the dose, the interval and anything done alongside it.
Rejuran delivers polynucleotides — long chains of nucleotides purified from salmon DNA — into the skin with fine microinjections. PN is thought to support the skin’s own repair environment, helping to improve hydration, elasticity and fine texture over a series of sessions. The range is tailored to different needs: Healer for overall skin quality, HB with added hyaluronic acid for hydration and comfort, I for the delicate eye area, and S for depressed scars.

How it works
01
Polynucleotides from salmon DNA
Rejuran delivers polynucleotides (PN) — long chains of nucleotides purified from salmon DNA — into the skin with fine microinjections.
02
Supporting the skin’s repair environment
PN is thought to support the skin’s own repair environment rather than adding volume, helping the skin work on hydration, elasticity and fine texture.
03
A range for different needs
The formula is tailored: Healer for overall quality, HB with hyaluronic acid for hydration, I for the eye area, and S for depressed scars.
04
Built over a series
Because it works with the skin’s own processes, changes develop across a series of sessions rather than at once. (Results vary by individual.)
The same treatment, never the same plan.
the qd standard
Rather than a fashionable name or a fixed package, we weigh the structure found at examination, safety, recovery and the limits within one plan.
- 01DIAGNOSIS FIRSTCause before nameWe first separate out the tissue and the function behind your concern.
- 02LESS, PRECISEOnly as much as neededRather than an excessive change, we plan the smallest scope with a clear role.
- 03HONEST LIMITThe limits, explained tooWe explain the change you can expect, the alternatives, individual differences and the risks.

From consultation to follow-up, planned as one flow.
personal plan
Rejuran is an injectable skin booster that uses polynucleotides (PN) purified from salmon DNA to support the skin’s own repair and improve texture, fine lines and elasticity. At QD Clinic in Gangnam, Seoul, we offer the Rejuran range — Healer, HB, I and S — and choose the formula and areas after assessing your skin. A session usually takes about 20–40 minutes including numbing. (Results vary by individual.)
Ingredients and authenticity
We check the product name, the maker, the ingredients, the expiry date and the use approved for that purpose.
Anatomy and expression
We look at where vessels are at risk, at muscle movement, skin thickness and the proportions of the whole face, then set the injection points.
Small amounts, one stage at a time
Allowing for swelling and the early response, we avoid overcorrection and top it up later if that is needed.
What the procedure is like
- Consultation and skin assessment
- Cleansing and numbing cream
- Microinjections across the treatment area
- Cooling, soothing and aftercare guidance
Time: A session takes about 20–40 minutes, including numbing time.
Please read this before treatment
- Little downtime; small raised bumps at the injection sites are common and usually settle within about 1–2 days.
- Temporary redness, mild swelling, tenderness or minor bruising may occur.
- Avoid makeup, saunas and intense exercise briefly, use sun protection, and follow the guidance we provide.
Safety & considerations
Possible reactions
- Small raised bumps at the injection sites, usually settling within about 1–2 days
- Temporary redness, mild swelling or a flushed feeling
- Tenderness in the treated area for a short time
- Occasionally minor bruising at injection points
When to take extra care
- Pregnancy or breastfeeding — let us know at consultation
- Active skin infection, inflammation or open lesions in the treatment area
- Known allergy or hypersensitivity, including to fish or salmon-derived products
- A history of keloid or difficulty with wound healing
- Recent injectables or energy treatments in the area — tell your doctor so timing can be planned
what to expect
What to expect over time
A general guide to how the days and months after treatment usually unfold. Results vary by individual.
DAY 0
Treatment day
Numbing first, then microinjections across the area. Small raised bumps at the injection sites are common, with mild redness or swelling.
DAY 1-2
Bumps settling
The small bumps usually settle within about 1–2 days; under-eye areas can take a little longer. Minor bruising, if any, starts to fade.
WEEK 1-3
Between sessions
Skin may begin to look a little smoother or brighter. Sessions are usually spaced 2–4 weeks apart.
1-3 MONTHS
Skin-quality change
Over the course and the following weeks, many people notice smoother texture and improved elasticity as collagen remodels. (Results vary by individual.)
AFTER THE COURSE
Review & maintenance
Your doctor reviews the outcome and discusses maintenance timing based on your skin.
Sessions & results
A typical plan is a course of about 3–4 sessions spaced roughly 2–4 weeks apart, with skin looking smoother and brighter gradually over the following weeks and fuller collagen remodeling over a few months. Maintenance is considered after a period decided at consultation. (Results vary by individual.)
how it compares
How it compares
These injectable skin boosters all support skin quality, but they use different materials and work in different ways, so they suit different goals.
| Rejuran | Juvelook | Re2O | |
|---|---|---|---|
| Main agent | Polynucleotides (from salmon DNA) | PDLLA microparticles + HA | ECM components (collagen, elastin, HA) |
| How it works | Supports the skin’s own repair | Prompts gradual collagen renewal | Supplies ready-made matrix as a scaffold |
| Often chosen for | Overall skin quality, fine lines | Texture, glow and subtle structure | Structural support, thin or crepey skin |
| Sessions | Usually a course of a few sessions | Usually a short course | Usually a short course |
| Downtime | Little; small bumps possible | Little; small papules possible | Little; small bumps possible |
Neither is “better” — they work differently and suit different goals. The right choice is decided after we assess your skin.
Before you decide, the questions people always ask
before consultation
Its main ingredient is polynucleotide (PN), DNA fragments obtained from salmon. Once placed in the skin, it works by supporting the process in which damaged tissue repairs itself. Unlike a filler, which adds volume to create shape, Rejuran works on the condition of the skin itself, so it is a different kind of treatment from one that changes how you look straight away.
Please be sure to tell us beforehand. The ingredient is purified, but if you have a history of allergy we weigh the decision to treat very carefully. Allergic reactions have been reported on rare occasions, so telling us exactly what you reacted to in the past and how it showed itself helps us judge.
As a rule we plan a course of three to four sessions three to four weeks apart, then look at how your skin responds and discuss maintenance from there. The number of sessions varies with skin condition and age, so we do not fix it in advance. Once a course is finished, we compare your skin with the photographs taken before you started and decide the next plan together.
Small raised areas where the product was injected are a common part of the course and usually flatten within a day or two. If a lump you can feel is still there after several days, however, or if it gradually grows, it may be a nodule and needs to be checked. If that happens, please do not rub it and contact us instead.
We choose according to your concern and the area being treated. Healer is used for overall texture and firmness; HB, which has hyaluronic acid added, when dryness comes with it; Eye for the thin skin under the eyes; and S, at a higher concentration, for indented scars. Rather than starting from a product name, it makes more sense to decide first what is troubling your skin the most right now.
The medical information on this page was reviewed by Hong Sahyeok, plastic surgeon and Medical Director of QD Clinic.
